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If you have been treated with Acthar for MS exacerbations and are willing to share your experience, please contact us and let us know your story.

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Acthar Patient FAQs

Find answers to common patient questions.

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Acthar Patient Resources

Patient resources are designed to help you understand MS and everything you need to know about Acthar.

Download Acthar Injection Instructions (Intramuscular Administration) (PDF - 1.2 MB)
Patient information on Acthar and how to intramuscularly inject it

Download Acthar Injection Instructions (Intramuscular Administration) (Español) (PDF - 1.5 MB)
El folleto para pacientes de Acthar en español

Download Acthar Injection Instructions (Subcutaneous Administration) (PDF - 4 MB)
Patient information on Acthar and how to subcutaneously inject it

Download Acthar Injection Instructions (Subcutaneous Administration) (Español) (PDF - 3 MB)
El folleto para pacientes de Acthar en español

Download Waiting Room Brochure (PDF - 1.0 MB)
The basics of MS exacerbations and how Acthar can help

Download Waiting Room Brochure (Español) (PDF - 1.0 MB)
La guía del medicamento Acthar en español

A variety of internet sites that provide basic information about multiple sclerosis and multiple sclerosis patient support resources are available. Links to representative sites are listed below.

Unlike IV steroids, Acthar allows me to be at home while receiving treatment for my MS exacerbations. I think that people always seem to heal much better at home rather than in the hospital.

- Patient treated for MS exacerbations with Acthar

Questcor

Uses

H.P. Acthar^® Gel (repository corticotropin injection) is an adrenocorticotropic hormone (ACTH) analogue used for:

Monotherapy treatment of infantile spasms (IS) in infants and children under 2 years of age.
The treatment of exacerbations of multiple sclerosis in adults.
For inducing a diuresis or a remission of proteinuria in the nephrotic syndrome without uremia of the idiopathic type or that due to lupus erythematosus.
The following: rheumatic disorders; collagen diseases; dermatologic diseases; allergic states; ophthalmic diseases and respiratory diseases.

Important Safety Information

Patients, parents, and caregivers should be aware of the important information about H.P. Acthar^® Gel.

Acthar should never be given intravenously (into a vein). Acthar should not be used in patients with a skin condition called scleroderma, bone density loss (osteoporosis), infection throughout the body, eye infection called ocular herpes simplex, recent surgery, history of or a current stomach ulcer, heart problems, high blood pressure, or allergy to pig-derived proteins. Tell your doctor about any health problems or medicines.

Acthar may cause side effects similar to side effects that happen due to treatment with steroid medicines. Not all of these side effects have occurred with Acthar but they may occur. Acthar is a medicine that affects a patient’s immune system, and therefore patients may be more likely to get new infections, or inactive infections may become active. Acthar has effects on the adrenal gland. When a patient is taking Acthar, their adrenal gland may produce too much of a hormone called cortisol. This can cause symptoms of Cushing’s syndrome (upper body fat, rounded face, thin skin), which is more common in patients who take this medicine for a long time. When a patient stops taking Acthar after a long time, the body may not produce enough cortisol on its own (adrenal insufficiency). The doctor may prescribe a steroid medicine to protect the body until the adrenal gland recovers. Do not stop administering Acthar without talking to your doctor first. Blood pressure should be checked during treatment, and your doctor may instruct you to make some dietary changes. Patients should not receive certain vaccines during treatment with Acthar. Talk to your doctor about which vaccines are safe for use. Acthar may hide (or mask) symptoms of other conditions or diseases and it may be more difficult for your doctor to diagnose other conditions or diseases in you or your child during treatment. The person receiving Acthar has an increased risk for bleeding from the stomach or having a stomach ulcer. Inform your doctor about any pain in the stomach area, bloody vomit, or bloody or black stools. While on Acthar changes in mood and behavior such as irritability, depression, or trouble sleeping, may occur.

Other side effects are possible. Acthar may make certain other medical conditions worse, such as diabetes (may increase blood sugar); cause eye problems, such as cataracts, increased pressure in the eye (glaucoma), and possible damage to the optic nerve; and cause allergic reactions to Acthar (seen as skin rash, swelling of the face, tongue, lips, or throat, and trouble breathing). Acthar may affect growth and physical development after long term use. Long term use of Acthar may cause an increase in the size of the heart, but this condition usually goes away after Acthar is stopped.

The most common side effects of Acthar in infants include: infections, increased blood pressure, irritability and changes in behavior, changes in appetite and weight, diarrhea, and vomiting. Other adverse reactions reported in adults and children over 2 years of age included: abdominal bloating, anxiety, asthma, chest discomfort, congestive heart failure, dizziness, shortness of breath, redness of the face, fluid retention, flushing, headache, injection site pain, tiredness, muscle weakness, nervousness, rapid heart rate and lack of energy. Tell your doctor if there is any side effect that bothers you or your child or that does not go away. These are not all of the possible side effects of Acthar. For more information, ask your doctor, nurse, or pharmacist or call 1-800-465-9217. You may report side effects to the FDA at 1-800-FDA-1088.

For a full list of warnings, precautions, and adverse events related to Acthar, please refer to the full Prescribing Information and discuss this information with your healthcare provider.

H.P. Acthar^® Gel and Questcor^® are registered trademarks of Questcor Pharmaceuticals, Inc.